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I don't know if the word "charted" really applies but it was first explored by the Quadros-1 probe in the 22nd century.


If the quadrant was ever charted I'd say it wouldhave had to occur during or shortly after the Dominion War. The DS9 crew seemed to regularly get lost, not to mention the fact I can't the Founders allowing people to run around exploring their territory. The fact the Romulan/Cardassian force in "The Die is Cast" didn't really know where the Founder's homeworld for some time suggests that the quadant could have only been partially charted at most.

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