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The Enterprise B was launched from an Earth drydock in 2293. According to Memory Alpha, the Star Trek wiki, no retire date is given. However, the Enterprise C is launch several years before 2344 (when it responds to a Klingon distress call and is destroyed) and it could have taken anywhere up to 5 years to build, so the Enterprise B wasn't in service much more than 20 or 30 years, though whether it was simply retired from service, refitted to be a fleet runner as seen in The Next Generation (e.g USS Hood) or is destroyed is unknown.

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