At least in canon, it is. The Enterprise-D was commissioned and launched shortly before the events of "Encounter at Farpoint", rendering that statement incorrect.
it is likely that you missread the passage. Dr. Crusher did not set foot on Enterprise until the events of Encounter at Farpoint.
Crusher and Picard knew each other from the Stargazer. Picard send Crusher's husband on a mission where he died. He later took her to see the body. From Wesley's statement's this was roughly 12 years before Farpoint.