She dies many times in the course of Voyager, though this is always in alternate timelines. She holds the record for most deaths in any series, at 9.
The last time she is seen in canon is as an Admiral in Star Trek Nemesis. It is her that gives Picard the order to meet with the new Romulan Praetor Shinzon.
Although I think it is considered non-canon, she is mentioned a few times in Star Trek Online as one of the first people to investigate the supernova of 2387 that destroys Romulus. It is also mentioned that she commands Voyager on the mission.
Also non-canon, she is taken by the Borg, in 2380 and made into the new Queen. She is rescued by Seven of Nine and the Collective is completely destroyed. She is apparently killed in the event, though she is mentioned to a travelling companion to Lady Q. Despite this, she is mentioned as being definitely dead.